Case Report | Open Access | 10.31586/Surgery.0302.06

Primary Malignant Cardiac Tumors (PMCTs) Successful Resection of a Huge Liposarcoma of the Heart

  • S Zeratiyan1, M Mesbah2, MA Yousefnia3, N Jalilifar1, AJ Khamooshi3 and D Pazook1,4,*
    1
    Department of Surgery and Cardiovascular & Thoracic surgery, Hazrat Rasol Akrm Hospital, Iran University, Iran
    2
    Department of Cardiovascular & Thoracic anaesthesia, Hazrat Rasol Akrm Hospital, Iran University, Iran
    3
    Shahid Rajaei Cardiovascular Surgery Center, Iran
    4
    Department of Surgery, Sahlgrenska University Hospital, Sweden

Abstract

Primary cardiac tumors are rare with an incidence ranging from 0.001% to 0.03% in autopsy series. The prognosis of cardiac sarcomas remains poor because it proliferates rapidly, and distant metastases are often found at diagnosis. We present a case of liposarcoma in the atrium of the heart as case report and same time,we do a literature review about it.Case Report: We present the case of a 30-year-old female with a significant tumor of cardiac liposarcoma, with chief complaint of dyspnea, tachycardia and heart failure even angina pectoris.Conclusion: The diagnostician?s differential diagnosis must be broad when encountering common chief complaints, such as tachycardia, heart failure and angina pectoris.
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Reference

[1]
Guilherme H. Oliveira, MD*; Sadeer G. Al-Kindi, MD*; Christopher Hoimes, DO; Soon J. Park, MD Characteristics and Survival of Malignant Cardiac Tumors A 40-Year Analysis of >500 Patients (Circulation. 2015;132:2395-2402. DOI: 10.1161/CIRCULATIONAHA.115.016418.)
[2]
Cristina Basso, Stefania Rizzo, Marialuisa Valente, Gaetano Thiene, Prevalence and pathology of primary cardiac tumours. Cardiovascular Medicine 2012;15(1):18?29
[3]
Vander Salm TJ.Unusual primary tumors of the heart. Semin Thorac Cardiovasc Surg.2000 Apr;12(2):89-100.
[4]
Elizabeth S. Ellent, MD,1 Ronald Chong-Yik, MD, MPH,1,2 Abdul Mukhtadir Khan, MD3. Metastatic Cardiac Angiosarcoma in a 26-Year-Old Male. Ochsner Journal 16:324?328, 2016
[5]
Freedom RM, Lee KJ, MacDonald C, Taylor G. Selected aspects of cardiac tumors in infancy and childhood. Pediatr Cardiol. 2000;21:299? 316.
[6]
Song Y, Hu R, Yao Q. Pathological analysis of 268 cases of tumors in the heart and the pericardium. J SUN Yat-sen-Univ (Med Sci) 2003;24:197? 201.
[7]
Roberts WC. Primary and secondary neoplasms of the heart. Am J Cardiol. 1997;80:671?82.
[8]
Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastasis. J Clin Pathol. 2007;60:27?34.
[9]
Hanfling SM. Metastatic cancer to the heart. Review of the literature and report of 127 cases. Circulation. 1960;22:474?83.
[10]
Thomas-de-Montpr?ville V, Nottin R, Dulmet E, Serraf A. Heart tumors in children and adults: clinicopathological study of 59 patients from a surgical center. Cardiovasc Pathol. 2007;16:22?8.
[11]
Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastasis. J Clin Pathol. 2007;60:27?34.
[12]
Travis WT, Brambilla E, Muller-Hermelink HK, Harris CC, eds. Pathology and genetics of tumours of the lung, pleura and heart. World Health Organisation Classification of tumours. Lyon: IARC; 2004.
[13]
Reynen K. Cardiac myxomas. N Engl J Med. 1995;33:1610?7.
[14]
Basso C, Valente M, Casarotto D, Thiene G. Cardiac lithomyxoma. Am J Cardiol. 1997;80:1249?51.
[15]
Burke AP, Virmani R. Cardiac myxoma: a clinicopathologic study. Am J Clin Pathol. 1993;100:671?80.
[16]
Edwards FH, Hale D, Cohen A, Thompson L, Pezzella AT, Virmani R. Primary cardiac valve tumors. Ann Thorac Surg. 1991;52:1127?31.
[17]
Sun JP, Asher CR, Yang XS, Cheng GG, Scalia GM, Massed AG, et al. Clinical and echocardiographic characteristics of papillary fibroelastomas: a retrospective and prospective study in 162 patients. Circulation. 2001;103:2687?93.
[18]
Basso C, Bottio T, Valente M, Bonato R, Casarotto D, Thiene G. Primary cardiac valve tumours. Heart. 2003;89:1259?60.
[19]
Gowda RM, Khan IA, Nair CK, Mehta NJ, Vasavada BC, Sacchi TJ. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003;146:404?10.
[20]
Valente M, Basso C, Thiene G, Bressan M, Stritoni P, Cocco P, Fasoli G. Fibroelastic papilloma: a not-so-benign cardiac tumor. Cardiovasc Pathol. 1992;1:161?6.
[21]
Cunningham KS, Veinot JP, Feindel CM, Butany J. Fatty lesions of the atria and interatrial septum. Hum Pathol. 2006;37:1245?51.
[22]
Brizard C, Latremouille C, Jebara VA, Acar C, Fabiani JN, Carpentier AF. Cardiac hemangiomas. Ann Thorac Surg. 1993;56:390?4.
[23]
Kipfer B, Englberger L, Stauffer E, Carrel T. Rare presentation of cardiac hemangiomas. Ann Thorac Surg. 2000;70:977?9.
[24]
Uzun O, Wilson DG, Vujanic GM, Parsons JM, De Giovanni JV. Cardiac tumours in children. Orphanet J Rare Dis. 2007;2:11.
[25]
Chan HSL, Sonley MJ, Moes CAF, Daneman A, Smith CR, Martin DJ. Primary and secondary tumors of childhood involving the heart, pericardium and great vessels. A report of 75 cases and review of the literature. Cancer. 1985;56:825?36.
[26]
Beghetti M, Gow RM, Haney I, Maswon J, Williams WG, Freedom RM. Pediatric primary benign cardiac tumors: a 15-year review. Am Heart J. 1997;134:1107?14.
[27]
Becker, Anton E. Primary heart tumors in the pediatric age group: a review of salient pathologic features relevant for clinicians. Pediatr Cardiol. 2000;21:317?23.
[28]
Padalino MA, Basso C, Milanesi O, Vida VL, Moreolo GS, Thiene G, Stellin G. Surgically treated primary cardiac tumors in early infancy and childhood. J Thorac Cardiovasc Surg. 2005;129:1358?63.
[29]
Nir A, Tajik J, Freeman WK, et al. Tuberous sclerosis and cardiac rhabdomyoma. Am J Cardiol. 1995;76:419?21.
[30]
Kurian KK, Weisshaar D, Parekh H et al. Primary angiosarcoma: case report and review of the literature. Cardiovascular Pathology, 2006;15:110?2
[31]
Thiene G, Valente M, Lombardi M, Basso C. Tumours of the Heart. In: Camm JA, Luscher TF, Serruys PV, eds. ESC Textbook of Cardiovascular Medicine. Oxford: University Press; 2009.
[32]
Van Veer H, Meuris B, Verbeken E, Herijgers P. Primary atrial fibrosarcoma of the heart. Cardiovasc Pathol. 2008;17:325?8.
[33]
Basso C, Stefani A, Calabrese F, Fasoli G, Valente M. Primary atrial fibrosarcoma diagnosed by endocardial biopsy. Am Heart J. 1996;131:399? 402.
[34]
Mazzola A, Spano JP, Valente M, Gregorini R, Villani C, Di Eusanio M, et al. Leiomyosarcoma of the left atrium mimicking a left atrial myxoma. J Thorac Cardiovasc Surg. 2006;131:224?6.
[35]
Mazzucco A, Luciani GB, Bertolini P, Faggian G, Morando G, Ghimenton C. Primary leiomyosarcoma of the pulmonary artery: diagnostic and surgical implications. Ann Thorac Surg. 1994;57:222?5.
[36]
Burke AP, Rosada-de Christenson ML, Templeton PA, Virmani R. Cardiac fibroma: clinicopathologic correlates and surgical treatment. J Thorac Cardiovasc Surg. 1994;108:862?70
[37]
Warren WH. Malignancies involving the pericardium. Semin Thorac Cardiovasc Surg. 2000;12:119?29.
[38]
Luk A, Ahn E, Vaideeswar P, Butany JW. Pericardial tumors. Semin Diagn Pathol. 2008;25:47?53.
[39]
Bendek M, Ferenc M, Freudenberg N. Post-irradiation pericardial malignant mesothelioma: an autopsy case and review of the literature. Cardiovasc Pathol. 2010;19:377?9.
[40]
Yoshiyuki Yamashita, Kazuhiro Kurisu, Satoshi Kimura, and Yasutaka Ueno. Successful resection of a huge metastatic liposarcoma in the pericardium resulting in improvement of diastolic heart failure: a case report. Surg Case Rep. 2015 Dec; 1: 74. Published online 2015 Sep 2. doi: 10.1186/s40792-015-0079-4
[41]
Conklin LD, Reardon MJ. Autotransplantation of the heart for primary cardiac malignancy: development and surgical technique. Texas Heart Institute Journal. 2002;29(2):105.
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